Endocrine Abstracts

Introduction: Thyroid dysfunctions and autoimmunity may concur in the pathogenesis of hemostasis abnormalities. Hashimoto’s thyroiditis (HT) is a frequently chronic autoimmune disease in thyroid gland. The aim of our study were to comparison the hemostatic parameters in patients with HT and control subjects.Method: A total of 52 women were evaluated. Age, TSH, free T3, free T4, anti M, anti Tg, TAFI, TFPI, PAI-1, tPA, PF-4, fib...

A 44-year-old man with 6 months history of headache, fatique, depressive mood, anorexia, impotence, decreased libido, poliuria and polidypsia. The results of the physical examination were normal, except the patient had noduler guatr. Baseline hormonal investigations and dinamic tests showed panhypopituitarism and partial central diabetes insipidus. Magnetic resonance imaging (MRI) of the pituitary gland showed enlarged pituitary gland and a marked thickening (4.5 mm) of the in...

Aims: Impact of gestational diabetes mellitus on the coagulation system, dynamics involved at a pathophysiological level and the exact mechanism remain unclear.To evaluate association between diabetes-related parameters and haemostatic factors in order to search for a tendency of thrombosis in gestational diabetes mellitus.Methods and Material: Nineteen pregnant women who had gestational diabetes mellitus, 16 healthy pregnant and 1...

Aim: Diabetic rethinopathy is an important microvascular complication in diabetic patients. The association between hyperlipidemia and diabetic rethinopathy remains elusive. Lipoprotein associated phospholipase A2 (Lp-PLA2) is Ca independent serine kinase that hydrolyses oxidized LDL and forms lysilphoshotidylcholine and free fatty acid. The aim of the study was to determine serum levels of Lp-PLA2, traditional lipids, apolipoproteins in patients with diabetic rethinopathy and...